<p><em>Have we finally discovered the key to youthful energy, longevity, and cellular health?</em> </p><p>In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. </p><p>This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. </p><p>Here’s what you’ll learn in this episode: </p><p> • What Urolithin A is and its role in mitochondrial health and cellular energy production </p><p> • How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking </p><p> • The connection between mitochondrial dysfunction and immune system aging </p><p> • Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity </p><p> • Why mitochondrial support is critical for combating aging and improving overall performance </p><p> </p><p><strong>Resources:</strong>  </p><p> • <strong>2025 Biohacking Conference</strong> – <a href="https://biohackingconference.com/2025" rel="noopener noreferrer" target="_blank">https://biohackingconference.com/2025</a>  </p><p> • <strong>Timeline Nutrition -  </strong><a href="https://www.timeline.com/dave" rel="noopener noreferrer" target="_blank">https://www.timeline.com/dave</a> to get 10% off your first order  </p><p> • <strong>Timeline Instagram – </strong><a href="https://www.instagram.com/timeline_longevity/" rel="noopener noreferrer" target="_blank">https://www.instagram.com/timeline_longevity/</a>  </p><p> • <strong>Dave Asprey’s Website</strong> – <a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com</a>  </p><p> • <strong>Dave Asprey’s Book: Smarter Not Harder</strong> – <a href="https://daveasprey.com/books" rel="noopener noreferrer" target="_blank">https://daveasprey.com/books</a>  </p><p> • <strong>Danger Coffee</strong> – <a href="https://dangercoffee.com/" rel="noopener noreferrer" target="_blank">https://dangercoffee.com</a>  </p><p> • <strong>Danger Coffee Instagram</strong> – <a href="https://www.instagram.com/dangercoffeeofficial/" rel="noopener noreferrer" target="_blank">https://www.instagram.com/dangercoffeeofficial/</a>  </p><p> • <strong>Dave Asprey’s Linktree</strong> – <a href="https://linktr.ee/daveasprey" rel="noopener noreferrer" target="_blank">https://linktr.ee/daveasprey</a>  </p><p> • <strong>Upgrade Collective: Join The Human Upgrade Podcast Live</strong> – <a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a>  </p><p> • <strong>Own an Upgrade Labs</strong> – <a href="https://ownanupgradelabs.com/" rel="noopener noreferrer" target="_blank">https://ownanupgradelabs.com</a>  </p><p> • <strong>Upgrade Labs</strong> – <a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a>  </p><p> • <strong>40 Years of Zen – Neurofeedback training for advanced cognitive enhancement</strong> – <a href="https://40yearsofzen.com/" rel="noopener noreferrer" target="_blank">https://40yearsofzen.com</a>  </p><p><br></p><p><strong>Timestamps:</strong> </p><p> • <strong>00:00</strong> Introduction to Longevity and Mitochondria </p><p> • <strong>01:28</strong> The Role of Mitochondria in Immune Health </p><p> • <strong>03:36</strong> Understanding Inflammaging and Immune Aging </p><p> • <strong>07:47</strong> Measuring Immune Health and Inflammation </p><p> • <strong>13:33</strong> Urolithin A: A Mitochondrial Booster </p><p> • <strong>16:46</strong> Dosage and Effects of Urolithin A </p><p> • <strong>26:11</strong> Urolithin A and Exercise Performance </p><p> • <strong>28:31</strong> Urolithin A for Skin Health </p><p> • <strong>31:34</strong> Collagen and Aging: The Role of MMPs </p><p> • <strong>33:27</strong> Personal Experience with MMPs and Recovery </p><p> • <strong>35:04</strong> Measuring MMPs and Their Impact on Longevity </p><p> • <strong>36:18</strong> Skin Health and Urolithin A </p><p> • <strong>38:39</strong> Exploring Urolithin A’s Broader Benefits </p><p> • <strong>40:33</strong> Brain Health and Urolithin A </p><p> • <strong>43:33</strong> Combining Supplements for Optimal Health </p><p> • <strong>45:54</strong> Omega-3s and Mitochondrial Health </p><p> • <strong>46:51</strong> Ketones, MCTs, and Urolithin A </p><p> • <strong>54:30</stron