<p><strong>Your cells are starving. Not for food—but for oxygen.</strong> </p><p>In this episode of <em>The Human Upgrade</em>, Dave Asprey sits down with <strong>Dr. Jason Sonners</strong>, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. </p><p>You’ll learn how <strong>hyperbaric oxygen therapy (HBOT)</strong> triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. </p><p>This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. </p><p><br></p><p><strong>You’ll Learn:</strong> </p><p>• How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair </p><p>• Why mild-pressure chambers may be more powerful than you think</p><p>• What HBOT does to inflammation, brain fog, and biological aging markers </p><p>• How to stack HBOT with fasting, red light, and methylene blue for amplified results </p><p>• What Dr. Sonners’ PhD research reveals about oxygen pressure and genetic expression </p><p>• The truth about oxygen toxicity—and how to avoid the common mistakes </p><p>• How elite performers use HBOT for brain optimization, recovery, and resilience </p><p><br></p><p>** Get 30% of yourr tickets to the Biohacking conference by going to <a href="https://biohackingconference.com/2025" rel="noopener noreferrer" target="_blank">https://biohackingconference.com/2025</a> and use code ‘OXYHEALTH’ ** </p><p><br></p><p>Thank you to our sponsors!  </p><p>-Our Place | Head to <a href="https://fromourplace.com/" rel="noopener noreferrer" target="_blank">https://fromourplace.com/</a> and use the code DAVE for 10% off your order.  </p><p>-Timeline | Head to <a href="https://www.timeline.com/dave" rel="noopener noreferrer" target="_blank">https://www.timeline.com/dave</a> to get 10% off your first order. </p><p><br></p><p><strong>Resources:</strong>  </p><p>• <strong>Dave Asprey’s New Book - <em>Heavily Meditated</em>:</strong> <a href="https://daveasprey.com/heavily-meditated/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated/</a> </p><p><strong>• Jason's Website –  </strong><a href="https://usc-word-edit.officeapps.live.com/we/www.hbotusa.com" rel="noopener noreferrer" target="_blank">www.hbotusa.com</a> </p><p><strong>• OxyHealth Website: </strong><a href="https://www.oxyhealth.com/" rel="noopener noreferrer" target="_blank">https://www.oxyhealth.com/</a> </p><p>• <strong>2025 Biohacking Conference</strong>: <a href="https://biohackingconference.com/2025" rel="noopener noreferrer" target="_blank">https://biohackingconference.com/2025</a> </p><p>• <strong>Danger Coffee</strong>: <a href="https://dangercoffee.com/" rel="noopener noreferrer" target="_blank">https://dangercoffee.com</a> </p><p>• <strong>Dave Asprey’s Website</strong>: <a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com</a> </p><p>• <strong>Dave Asprey’s Linktree</strong>: <a href="https://linktr.ee/daveasprey" rel="noopener noreferrer" target="_blank">https://linktr.ee/daveasprey</a> </p><p>• <strong>Upgrade Collective – Join The Human Upgrade Podcast Live</strong>: <a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a> </p><p>• <strong>Own an Upgrade Labs</strong>: <a href="https://ownanupgradelabs.com/" rel="noopener noreferrer" target="_blank">https://ownanupgradelabs.com</a> </p><p>• <strong>Upgrade Labs</strong>: <a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a> </p><p>• <strong>40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement</strong>: <a href="https://40yearsofzen.com/" rel="noopener noreferrer" target="_blank">https://40yearsofzen.com</a> </p><p><br></p><p> <strong>Timestamps:</strong> </p><p>• <strong>00:00</strong> Trailer </p><p>• <strong>01:59</strong> Intro </p><p>• <strong>03:14</strong> New research on aging and oxygen </p><p>• <strong>05:39</strong> Mild vs. hard-shell chambers </p><p>• <strong>13:05</strong> HBOT for longevity and stem cells </p><p>• <strong>16:43</strong> How to optimize your sessions </p><p>• <strong>22:35</strong> Best therapies to stack with HBOT </p><p>• <strong>25:40</strong> Oxygen delivery and safety </p><p>• <strong>26:43</strong> Altitude and chamber effects </p><p>• <strong>30:01</strong> Key benefits of hyperbaric therapy </p><p>• <strong>34