<p>Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain’s power plants and keep you sharp all day long.</p><p><br></p><p>Chapters</p><p>0:00 – Introduction</p><p>0:22 – Brain energy vs dopamine</p><p>0:49 – ATP shortage causes fatigue</p><p>1:53 – Prefrontal cortex and energy</p><p>3:08 – Why ATP fuels focus and mood</p><p>4:40 – Stress, sleep and mitochondria</p><p>6:00 – Biohacks for energy production</p><p>7:39 – Backup battery: phosphagen system</p><p>8:46 – Creatine for brain energy & focus</p><p>13:18 – Vegans, women and creatine needs</p><p>15:07 – Best practices for dosing creatine</p><p>17:53 – Daily creatine + electrolytes</p><p><br></p><p><strong>Thank you to our sponsors!</strong></p><p>-ECHO Water | Go to <a href="http://echowater.com/dave" rel="noopener noreferrer" target="_blank">http://echowater.com/dave</a> and use code DAVE10 for 10% off your ECHO Flask.</p><p><br></p><p>Connect with Dave Asprey!</p><p><br></p><p>Website: https://daveasprey.com</p><p>TikTok: https://www.tiktok.com/@daveaspreyofficial</p><p>Instagram: https://www.instagram.com/dave.asprey/</p><p>Facebook: https://www.facebook.com/Daveaspreyofficial/</p><p>X: https://x.com/daveasprey</p><p>YouTube: https://www.youtube.com/c/daveaspreybpr</p><p><br></p><p>The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/</p><p><br></p><p>Danger Coffee: https://dangercoffee.com/DAVE15</p><p>Dave Asprey’s BEYOND Conference: https://beyondconference.com/</p><p>Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/</p><p>Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15</p><p>Upgrade Collective: https://www.ourupgradecollective.com</p><p>Upgrade Labs: https://upgradelabs.com</p><p>40 Years of Zen: https://40yearsofzen.com</p><p>See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.</p>