<p>Your brain has a gear you’ve never touched. Psychedelics can shift you into it. </p><p><br></p><p>In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. </p><p><br></p><p>You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave breaks down the latest research on psilocybin, brain plasticity, trauma release, and how to turn ancient compounds into modern performance tools. </p><p><br></p><p><strong>What You Will Learn in This Episode:</strong> </p><p>• How psychedelic shrooms unlock flow, focus, and creative power </p><p>• Why psilocybin boosts neuroplasticity, mood, and emotional healing </p><p>• Microdosing vs. full-dose: what works, when, and how </p><p>• How to stack psychedelics with nootropics and other biohacks </p><p>• The newest research on brain optimization and long-term benefits </p><p>• How to use psychedelics safely, strategically, and for real results </p><p>• Why shrooms may be the strongest mental upgrade in your toolkit </p><p><br></p><p>Thank you to our sponsors!  </p><p>-Quantum Upgrade | Go to <a href="https://quantumupgrade.io/Dave" rel="noopener noreferrer" target="_blank">https://quantumupgrade.io/Dave</a> for a free trial.  </p><p>-fatty15 | Go to <a href="https://fatty15.com/dave" rel="noopener noreferrer" target="_blank">https://fatty15.com/dave</a> and save an extra $15 when you subscribe with code DAVE. </p><p><br></p><p> <strong>Resources:</strong>  </p><p>• <strong>Dave Asprey’s New Book - <em>Heavily Meditated</em>:</strong> <a href="https://daveasprey.com/heavily-meditated/" rel="noopener noreferrer" target="_blank">https://daveasprey.com/heavily-meditated/</a> </p><p>• <strong>Matt’s Website –  </strong><a href="https://mattzemon.com/" rel="noopener noreferrer" target="_blank">https://mattzemon.com/</a> </p><p>• <strong>Matt's Instagram - </strong><a href="https://www.instagram.com/matt.zemon/" rel="noopener noreferrer" target="_blank">https://www.instagram.com/matt.zemon/</a> </p><p>• <strong>2025 Biohacking Conference</strong>: <a href="https://biohackingconference.com/2025" rel="noopener noreferrer" target="_blank">https://biohackingconference.com/2025</a> </p><p>• <strong>Danger Coffee</strong>: <a href="https://dangercoffee.com/" rel="noopener noreferrer" target="_blank">https://dangercoffee.com</a> </p><p>• <strong>Dave Asprey’s Website</strong>: <a href="https://daveasprey.com/" rel="noopener noreferrer" target="_blank">https://daveasprey.com</a> </p><p>• <strong>Dave Asprey’s Linktree</strong>: <a href="https://linktr.ee/daveasprey" rel="noopener noreferrer" target="_blank">https://linktr.ee/daveasprey</a> </p><p>• <strong>Upgrade Collective – Join The Human Upgrade Podcast Live</strong>: <a href="https://www.ourupgradecollective.com/" rel="noopener noreferrer" target="_blank">https://www.ourupgradecollective.com</a> </p><p>• <strong>Own an Upgrade Labs</strong>: <a href="https://ownanupgradelabs.com/" rel="noopener noreferrer" target="_blank">https://ownanupgradelabs.com</a> </p><p>• <strong>Upgrade Labs</strong>: <a href="https://upgradelabs.com/" rel="noopener noreferrer" target="_blank">https://upgradelabs.com</a> </p><p>• <strong>40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement</strong>: <a href="https://40yearsofzen.com/" rel="noopener noreferrer" target="_blank">https://40yearsofzen.com</a> </p><p><br></p><p><strong>Timestamps:</strong> </p><p>• 00:00 – Trailer </p><p>• 01:00 – Intro </p><p>• 06:01 – Personal Psychedelic Journeys </p><p>• 07:39 – Psychedelics and Self-Discovery </p><p>• 11:59 – Safe Use and Smart Navigation </p><p>• 29:09 – Psychedelics and Society </p><p>• 36:40 – Building Trust in the Process </p><p>• 37:14 – Facing Inner Fear </p><p>• 37:38 – Choice and Healing </p><p>• 37:51 – Diet and Conscious Decisions </p><p>• 38:55 – Judgment and Relationships </p><p>• 39:29 – Spirituality and Psychedelics </p><p>• 40:07 – The Entheogenic Reformation </p><p>• 41:29 – Past Lives and Expanded States </p><p>• 43:44 – Where Science Meets Spirituality </p><p>• 49:59 – Gratitude and Compassion in Healing </p><p>• 01:01:47 – The Power of Apologies </p><p>• 01:04:56 – Psychedelics in Therapy </p><p>• 01:08:57 – Final Thoughts on Psychedelics and Culture </p><p>See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.</p>